Equine Recurrent Uveitis (Moon Blindness): Clinical Signs and Pathogenesis
1. Moon Blindness (ERU) Equine Recurrent Uveitis (ERU), popularly referred to as Moon Blindness , is the most common cause of blindness in horses. The condition entails recurrent episodes of intraocular inflammation within the uveal tract consisting of the iris , ciliary body , and choroid . As opposed to superficial conjunctivitis, Moon Blindness is a deep-seated immune-mediated condition that causes permanent damage. Anatomy of Equine Uveitis: A comparative diagram illustrating the clinical manifestations of Moon Blindness. The right panel demonstrates corneal edema and a constricted pupil ( miosis ), highlighting the inflammation and pain associated with the disease. | VetInsight PK 2. Cause/Trigger of Moon Blindness The specific cause is often difficult to identify, but the following may precipitate the first episode: Infectious Agents: Most commonly caused by Leptospirosis ( Leptospira interrogans ). Immune-mediated response: Involves the development of an autoimmune...