VetInsight Pakistan

Introduction Canine Astrovirus (CaAstV), also known as Small Virus, is a small, non-enveloped, single-stranded RNA virus . It is often present in co-infections with Parvovirus or Coronavirus and is one of the main culprits in the Canine Infectious Diarrhea Complex . It is also one of the oldest viruses but still considered a "sneaky" disease that owners often do not even think of. the name "Astrovirus" comes from the Greek word 'astron' , meaning star, because of its shape under a microscope.  Transmission and Pathogenesis Canine Astrovirus is mainly spread by the fecal-oral method . Once it is ingested, it infects the mature enterocyte cells located at the tips of the microvilli in the intestine, leading to: Malabsorption Osmotic Diarrhea Villous Atrophy (shortening of the microvilli) Clinical Signs It is often subclinical in adult dogs but in puppies or immunocompromised dogs, the symptoms include: Watery Diarrhea Vomiting Lethargy and Anorexia Growth ...

Introduction While the news of Rabies and Parvovirus dominates the front pages of veterinary journals, a stealthy and cunning foe, Brucella canis , silently attacks breeding stock and poses a danger to the general public. As a Gram-negative, facultative, intracellular coccobacillus , Brucella canis is the primary causative agent of Contagious Abortion and Reproductive Failure in Dogs. But most importantly, it's a Zoonotic disease , meaning that it can leap from your loyal canine companions to you. Transmission The transmission of Brucella canis from one dog to another, or from a mother to a puppy, or even from a puppy to a human, is a complex and not yet fully understood subject. However, Brucella canis is a highly contagious disease and can be transmitted as follows: Oronasal contact Oro-Nasal transmission of vaginal discharge, aborted fetuses, or urine. Venereal Transmission Venereal transmission, i.e., from a female in heat to a male through coitus. Vertical transmission Vertic...

1.Introduction The Helicobacter genus comprises a wide range of bacteria that have adapted to survive in the extreme and acidic environment of the stomach. Though H. pylori is the primary focus of human gastroenterology, NHPH , including H. heilmannii , are increasingly recognized for their clinical relevance [1, 2].In domestic pets, H. heilmannii is notably prevalent in both symptomatic and clinically healthy animals. The zoonotic potential of H. heilmannii, or the ability to transmit the bacteria from pets to their owners, adds a multifaceted public health issue to the management of this microorganism. Though it is associated with chronic gastritis and even gastric cancer in humans, H. heilmannii is still an understudied microorganism in relation to the human-animal bond [1, 3]. 2. Prevalence and Pathogenesis in Pets It is a common inhabitant of the stomach of dogs and cats. Studies for its prevalence have yielded a range of 41 to 100 percent in healthy dogs and cats, and similar...

What is Canine Hepacivirus (CHV)? Everyone is aware of the serious liver infection known as Hepatitis C Virus (HCV). However, not many people are aware that their canine friends also carry a similar virus that causes serious infection in dogs. This virus is known as Canine Hepacivirus (CHV), and it is one of the most interesting discoveries in the field of veterinary science in recent times.Canine Hepacivirus was first detected in 2011 and is a 'cousin' of the Hepatitis C virus that infects humans. In fact, it is the closest relative of HCV among all animal viruses that have been detected so far.[1,2] Where Did it Come From? It is believed that Canine Hepacivirus and the Hepatitis C virus share a common ancestor that lived many centuries ago— between 500 and 1,000 years ago .[2,5] It is also believed that this virus was initially present in horses and was transmitted to dogs at a time when horses and dogs lived and worked together.[2,6] Is My Dog at Risk? The first thing to k...

What is Feline Calicivirus? If you have a cat, you have probably heard of the " cat flu ." It is a mild respiratory infection with symptoms of sneezing, runny eyes, and possibly a few mouth ulcers. Cats usually get over it quickly with a little tender loving care. But there is a darker side to this common disease that every cat owner should be aware of: Virulent Systemic Feline Calicivirus . The Deadly Mutation: From Nuisance to Killer VS-FCV is not a new virus but rather a highly aggressive and mutated form of a common feline virus known as calicivirus . This virus is like the 'super-powered' flu virus because while the flu virus infects only the nose and throat areas, this mutated form infects the entire body. This includes the blood vessels and internal organs [1, 2].What is so scary about this virus? This virus is highly contagious and has a mortality rate up to 50% or more. This virus puts healthy, vaccinated adult cats at risk as well. Signs of the Systemic Form...

1. Introduction The Canine Infectious Respiratory Disease Complex (CIRDC) is a complex condition caused by a variety of viral and bacterial infections. Traditionally, scientific research into CIRDC has concentrated on more familiar viral and bacterial infections, for example, Bordetella bronchiseptica and Canine Parainfluenza Virus . Nevertheless, the discovery of Canine Pneumovirus (CnPnV) in 2010 has opened a new chapter in the complex aetiology of CIRDC [1,2]. CnPnV is a Pneumoviridae virus related to Murine Pneumovirus and Human Respiratory Syncytial Virus (HRSV). Despite the disease potential of CnPnV, this viral infection is frequently not considered in routine veterinary diagnosis. The emergence of CnPnV as a clinically important disease entity, especially in high-density populations such as animal shelters and rehoming centres, suggests a more comprehensive approach to the complex aetiology of CIRDC [1,3]. 2. Viral Characterization and Pathogenesis CnPnV is an enveloped, s...