VetInsight Pakistan

1. Introduction The canine viral gastroenteritis is undergoing dynamic changes with the detection of new viral pathogens. Among these, Canine Kobuvirus ( CaKoV ) has been recognized as an important, though poorly studied, agent in canine viral gastroenteritis. Though Canine Parvovirus (CPV) and Canine Coronavirus (CCoV) are recognized as major viral pathogens in canine viral gastroenteritis, the detection rate of CaKoV in infected dogs indicates that it is probably playing an active role in canine enteric viral disease. 2. Viral Taxonomy and Genetic Diversity CaKoV is classified as a member of the Kobuvirus genus in the family Picornaviridae . The viral genome is 8.2 kb in length and consists of a single open reading frame (ORF) that codes for a polyprotein that is subsequently cleaved into structural and non-structural proteins.  • Genetic Characterization:  The viral genome has been found to possess considerable genetic diversity . The detection of unique viral lineages in...

Introduction While the news of Rabies and Parvovirus dominates the front pages of veterinary journals, a stealthy and cunning foe, Brucella canis , silently attacks breeding stock and poses a danger to the general public. As a Gram-negative, facultative, intracellular coccobacillus , Brucella canis is the primary causative agent of Contagious Abortion and Reproductive Failure in Dogs. But most importantly, it's a Zoonotic disease , meaning that it can leap from your loyal canine companions to you. Transmission The transmission of Brucella canis from one dog to another, or from a mother to a puppy, or even from a puppy to a human, is a complex and not yet fully understood subject. However, Brucella canis is a highly contagious disease and can be transmitted as follows: Oronasal contact Oro-Nasal transmission of vaginal discharge, aborted fetuses, or urine. Venereal Transmission Venereal transmission, i.e., from a female in heat to a male through coitus. Vertical transmission Vertic...